Kazuo Chin Selected Research

Bleomycin (Blenoxane)

1/2021	Profibrotic function of pulmonary group 2 innate lymphoid cells is controlled by regnase-1.
1/2013	Clinical relevance of plasma prostaglandin F2α metabolite concentrations in patients with idiopathic pulmonary fibrosis.
12/2009	Prostaglandin F(2alpha) receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-beta.
3/2004	The plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism.

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Kazuo Chin Research Topics

Disease

24	Obstructive Sleep Apnea 12/2021 - 03/2003
20	Asthma (Bronchial Asthma) 11/2016 - 10/2003
16	Interstitial Lung Diseases (Interstitial Lung Disease) 03/2022 - 01/2010
14	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 06/2004
13	Sleep Apnea Syndromes (Sleep Apnea) 01/2022 - 02/2013
10	Idiopathic Pulmonary Fibrosis 03/2022 - 12/2009
9	Inflammation (Inflammations) 11/2016 - 04/2004
8	Apnea 05/2019 - 06/2004
7	Respiratory Insufficiency (Respiratory Failure) 07/2022 - 01/2010
7	Dyspnea (Shortness of Breath) 04/2021 - 03/2010
7	Hypoxia (Hypoxemia) 12/2020 - 02/2005
6	Sleepiness 01/2017 - 05/2004
5	Cardiovascular Diseases (Cardiovascular Disease) 12/2021 - 01/2013
5	Fibrosis (Cirrhosis) 01/2021 - 03/2004
5	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2021 - 03/2004
5	Cough 05/2017 - 04/2007
4	Hypertension (High Blood Pressure) 12/2020 - 01/2009
4	Obesity 06/2020 - 11/2008
4	Hypercapnia 01/2020 - 02/2005
4	Cough-Variant Asthma 01/2012 - 03/2006
3	Pneumonia (Pneumonitis) 08/2018 - 02/2005
3	Idiopathic Interstitial Pneumonias 08/2018 - 08/2011
3	Weight Gain 10/2016 - 11/2008
3	Respiratory Sounds (Crackle) 03/2009 - 03/2006
2	COVID-19 07/2022 - 09/2021
2	Type 2 Diabetes Mellitus (MODY) 01/2021 - 08/2012
2	Hepatopulmonary Syndrome 12/2020 - 02/2011
2	Lung Injury 12/2020 - 06/2011
2	Respiratory Tract Diseases (Respiratory Tract Disease) 06/2020 - 05/2010
2	Dermatomyositis (Dermatopolymyositis) 03/2019 - 01/2017
2	Pneumothorax 08/2018 - 01/2011
2	Connective Tissue Diseases (Connective Tissue Disease) 08/2018 - 01/2017
2	Body Weight (Weight, Body) 01/2016 - 03/2012
2	Hypoventilation 11/2015 - 03/2003
2	Emphysema 09/2015 - 01/2013
2	Insulin Resistance 01/2015 - 04/2003
2	Hyperemia 01/2015 - 02/2013
2	Abdominal Obesity 01/2015 - 01/2015
2	Obesity Hypoventilation Syndrome (Pickwickian Syndrome) 11/2014 - 03/2003
2	Respiratory Hypersensitivity 01/2012 - 01/2011
2	Bronchiectasis 08/2011 - 04/2004
2	Chronic Cough 01/2011 - 03/2009
2	Disease Progression 09/2010 - 12/2009
2	Airway Remodeling 05/2010 - 03/2008
2	Disorders of Excessive Somnolence (Hypersomnia) 01/2006 - 05/2004
2	Pulmonary Atelectasis 02/2005 - 11/2004
1	Cross Infection (Nosocomial Infection) 09/2021
1	Pulmonary Hypertension 03/2021

Drug/Important Bio-Agent (IBA)

15	Oxygen (Dioxygen)IBA 01/2022 - 01/2009
11	Biomarkers (Surrogate Marker)IBA 12/2021 - 01/2011
5	Carbon MonoxideIBA 08/2018 - 09/2010
5	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2010 - 06/2004
4	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 08/2012
4	Bleomycin (Blenoxane)FDA LinkGeneric 01/2021 - 03/2004
4	SteroidsIBA 09/2015 - 10/2003
4	Methacholine Chloride (Methacholine)FDA Link 01/2012 - 11/2006
3	Carbon DioxideIBA 04/2021 - 11/2014
3	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 03/2021 - 03/2010
3	Proteins (Proteins, Gene)FDA Link 06/2020 - 12/2009
3	Matrix Metalloproteinases (MMPs)IBA 03/2019 - 04/2004
3	Immunoglobulin E (IgE)IBA 05/2017 - 04/2009
3	AntibodiesIBA 01/2017 - 08/2011
3	Triglycerides (Triacylglycerol)IBA 01/2015 - 04/2003
3	AllergensIBA 11/2014 - 10/2007
3	ProstaglandinsIBA 01/2013 - 12/2009
3	Capsaicin (Zostrix)FDA Link 01/2012 - 04/2007
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2020 - 01/2011
2	Hypnotics and Sedatives (Sedatives)IBA 06/2017 - 01/2017
2	AutoantibodiesIBA 01/2017 - 08/2011
2	LeptinIBA 01/2016 - 04/2003
2	Hormones (Hormone)IBA 01/2016 - 01/2016
2	GhrelinIBA 01/2016 - 11/2008
2	Lipocalin-2IBA 06/2014 - 01/2013
2	LipocalinsIBA 12/2013 - 01/2013
2	CytokinesIBA 05/2013 - 01/2012
2	CholesterolIBA 02/2013 - 01/2006
2	Bronchodilator Agents (Bronchodilators)IBA 01/2012 - 03/2009
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 05/2010 - 03/2008
2	CollagenIBA 12/2009 - 01/2009
1	AlbuminsIBA 01/2022
1	SaltsIBA 12/2021
1	DiureticsIBA 12/2021
1	Chemokine CCL27IBA 06/2021
1	Fibrinogen (Factor I)FDA Link 06/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	FHDIBA 01/2021

Therapy/Procedure

21	Therapeutics 01/2022 - 03/2003
18	Continuous Positive Airway Pressure 01/2022 - 03/2003
14	Noninvasive Ventilation 07/2022 - 05/2005
10	Lung Transplantation 03/2022 - 08/2014
6	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 12/2020 - 11/2004
4	Aftercare (After-Treatment) 08/2015 - 04/2003
3	Artificial Respiration (Mechanical Ventilation) 12/2020 - 11/2004
3	Liver Transplantation 02/2011 - 02/2005
2	Transplantation 03/2022 - 02/2011
2	Cannula 09/2021 - 12/2020
2	Hematopoietic Stem Cell Transplantation 03/2021 - 08/2018
2	Hepatectomy 01/2009 - 03/2005
1	Mechanical Ventilators (Ventilator) 07/2022
1	Respiratory Therapy (Therapy, Respiratory) 12/2020